Effect of FK 506 chronic administration on bromosulphthalein hepatic excretion in rats.
نویسندگان
چکیده
THERE are several reports dealing with the hepatic effect of FK 506,1-4 some of which are beneficial while others are adverse. Because the liver is a major target organ that is often the site of drug toxicity, studies directed at determining whether FK 506 affects specific hepatic function and/or its histologic appearance are important. Therefore, the present study was undertaken to examine bromosulphthalein (BSP) elimination kinetics in rats as a sensitive index of hepatic excretory function under the influence of FK 506 in the rat.
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ورودعنوان ژورنال:
- Transplantation proceedings
دوره 23 6 شماره
صفحات -
تاریخ انتشار 1991